PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells
PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells
Key Points PKR may be an unrecognized but important regulator of HSPC cell fate. PKR expression regulates the frequency of HSPCs in the bone marrow and their response to stress.
- University of Florida United States
Male, Mice, Knockout, Blotting, Western, Cell Cycle, Apoptosis, Cell Differentiation, Mice, Transgenic, Flow Cytometry, Hematopoietic Stem Cells, Mice, Inbred C57BL, Mice, Animals, Cytokines, Humans, Female, RNA, Messenger, Bone Marrow Diseases, Cells, Cultured, Cell Proliferation, Genes, Dominant
Male, Mice, Knockout, Blotting, Western, Cell Cycle, Apoptosis, Cell Differentiation, Mice, Transgenic, Flow Cytometry, Hematopoietic Stem Cells, Mice, Inbred C57BL, Mice, Animals, Cytokines, Humans, Female, RNA, Messenger, Bone Marrow Diseases, Cells, Cultured, Cell Proliferation, Genes, Dominant
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