Chromosomal Assignment of Three Novel Mouse Genes Expressed in Testicular Cells
Copyright policy )Chromosomal Assignment of Three Novel Mouse Genes Expressed in Testicular Cells
The chromosomal positions of three genes that are selectively expressed in mouse testis cells have been identified. These genes include (i) TAZ83, which codes for an early- to mid-pachytene germ cell stage-expressed, cysteine-rich transmembrane protein (cyritestin) with homologies to various snake toxins and guinea pig sperm-egg fusion proteins; (ii) TNZ1, which is expressed in neonatal Leydig cells; and (iii) TAZ4, a testis-specific gene isolated by immunoscreening with antiserum raised against Sertoli cell membranes. Our experimental data, derived from chromosomal in situ hybridizations and RFLP studies of genetic backcrosses, indicate that (i) the TAZ83 (cyritestin) gene maps to chromosome 8, band A2, near the Plat locus; (ii) TNZ1 is located in the proximal region of chromosome 11; and (iii) TAZ4 is located at band D in the distal portion of chromosome 11, near the Hlr1 locus, with a related sequence, TAZ4-rs1, in the proximal part of chromosome 1.
- Heinrich Heine University Düsseldorf Germany
- Yale University United States
- University of Duesseldorf Germany
- Jackson Laboratory United States
Male, Base Sequence, Transcription, Genetic, Molecular Sequence Data, Chromosome Mapping, Gene Expression, Blotting, Northern, Polymerase Chain Reaction, Mice, Inbred C57BL, Blotting, Southern, Mice, Organ Specificity, Testis, Animals, DNA Probes, Spleen, DNA Primers
Male, Base Sequence, Transcription, Genetic, Molecular Sequence Data, Chromosome Mapping, Gene Expression, Blotting, Northern, Polymerase Chain Reaction, Mice, Inbred C57BL, Blotting, Southern, Mice, Organ Specificity, Testis, Animals, DNA Probes, Spleen, DNA Primers
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).31 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!