Nature Reviews Molecular Cell Biology
Article . 2001 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
Evolutionary conservation between budding yeast and human kinetochores
Authors: K, Kitagawa; P, Hieter;
doi: 10.1038/35089568
pmid: 11533725
Evolutionary conservation between budding yeast and human kinetochores
Abstract
Accurate chromosome segregation during mitosis requires the correct assembly of kinetochores--complexes of centromeric DNA and proteins that link chromosomes to spindle microtubules. Studies on the kinetochore of the budding yeast Saccharomyces cerevisiae have revealed functionally novel components of the kinetochore and its regulatory complexes, some of which are highly conserved in humans.
Related Organizations
- University of British Columbia Canada
- St. Jude Children's Research Hospital United States
Keywords
Evolution, Molecular, Chromosome Segregation, Yeasts, Humans, Spindle Apparatus, Kinetochores, Phylogeny
Evolution, Molecular, Chromosome Segregation, Yeasts, Humans, Spindle Apparatus, Kinetochores, Phylogeny
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citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
100
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