Resumen del póster presentado al 7th International Franco-Spanish Workshop on Bio-Inorganic Analytical Chemistry, celebrado en Gijón (España) del 1 al 3 de julio de 2012. Selenium (Se) has a well-known role in prevention of chronic discases associated with oxidative stress and inflammation. Hundreds of millions of people worldwide do not reach the ROA of selenium and consumption of Se supplements has been the most widespread approach to prevent Se deficiency. Several authors have reported preparation of Se-enriched foods by fermentation processes. Sauerkraut, a popular product resulting from the lactic acid fermentation of white cabbage, is a valuable food, due to its nutritional and health-promoting properties, mainly attributed to its high content of antioxidant compounds, such as vitamin C and phenolic compounds which prevent cell damage caused by free radicals. The objective of this study was to produce Se-enriched sauerkraut and to study the effect of selenite addition on indole glucosinolate hydrolysis products (GLS), vitamin C, Se biotransfomation and antioxidant activity of sauerkraut. For this purpose, white cabbage was naturally fermented with 0.14 mg Se/kg fresh cabbage (NFSe), as sodiun selenite, or without Se addition (NF). Total Se content was measured by JCPMS and coupled to HPLC (anion exchange and reverse phase chromatography) for Se species analysis. Se total reached up to 1.29 u/g d.m. (0.11.ug/g f.m.). Selenomethylselenocysteine (SeMcSeCys) was the primary seleno compound detected in Se-enriched sauertkraut. The addition of Na2Se03 during fermentation enhanced the formation of some GLS breakdown compounds when compared to NF cabbages. No previous studies have been found on the effect of Se on the formation of GLS hydrolysis products. Indole GLS breakdown products are considered anticarcinogenic agents that are associated with antioxidant and anti-inflamatory activities. NFSe cabbage extracts showed higher (P < 0.05) antioxidant activity 163 umol trolox/g d. m.) than did NF extracts. On the other hand, the use of selenite as Se-enriched isotopo for Se-enriched saucrkraut preparation has allowed us to easily obtain SeMeSeCys. This important seleno compound, once isolated, can be used for performing species-specific IDA analysis or for tracing the metabolic pathway of this compound in living organisms. Peer reviewed