Erp1p and Erp2p, Partners for Emp24p and Erv25p in a Yeast p24 Complex
Copyright policy )Erp1p and Erp2p, Partners for Emp24p and Erv25p in a Yeast p24 Complex
Six new members of the yeast p24 family have been identified and characterized. These six genes, named ERP1–ERP6 (for Emp24p- and Erv25p-related proteins) are not essential, but deletion ofERP1 or ERP2 causes defects in the transport of Gas1p, in the retention of BiP, and deletion ofERP1 results in the suppression of a temperature-sensitive mutation in SEC13 encoding a COPII vesicle coat protein. These phenotypes are similar to those caused by deletion of EMP24 orERV25, two previously identified genes that encode related p24 proteins. Genetic and biochemical studies demonstrate that Erp1p and Erp2p function in a heteromeric complex with Emp24p and Erv25p.
- National Research Council Canada Canada
- University of California, Berkeley United States
- Howard Hughes Medical Institute United States
- National Academies of Sciences, Engineering, and Medicine United States
- University of Hertfordshire United Kingdom
Saccharomyces cerevisiae Proteins, Base Sequence, Genes, Fungal, Molecular Sequence Data, Vesicular Transport Proteins, Membrane Proteins, Biological Transport, Fungal Proteins, Phenotype, Yeasts, Mutation, pharmaceutical, HSP70 Heat-Shock Proteins, Amino Acid Sequence, Carrier Proteins, Gene Deletion
Saccharomyces cerevisiae Proteins, Base Sequence, Genes, Fungal, Molecular Sequence Data, Vesicular Transport Proteins, Membrane Proteins, Biological Transport, Fungal Proteins, Phenotype, Yeasts, Mutation, pharmaceutical, HSP70 Heat-Shock Proteins, Amino Acid Sequence, Carrier Proteins, Gene Deletion
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).178 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
Citations provided by BIP!Popularity provided by BIP!