Targeting Viral Surface Proteins through Structure-Based Design
Copyright policy )Targeting Viral Surface Proteins through Structure-Based Design
The emergence of novel viral infections of zoonotic origin and mutations of existing human pathogenic viruses represent a serious concern for public health. It warrants the establishment of better interventions and protective therapies to combat the virus and prevent its spread. Surface glycoproteins catalyzing the fusion of viral particles and host cells have proven to be an excellent target for antivirals as well as vaccines. This review focuses on recent advances for computational structure-based design of antivirals and vaccines targeting viral fusion machinery to control seasonal and emerging respiratory viruses.
- UNIVERSITY OF GEORGIA
- University of Georgia Press United States
- University of Georgia United States
- University of Georgia Georgia
- Institute of Bioinformatics India
Clinical Trials as Topic, rational design, Viral Vaccines, Review, Microbiology, Antiviral Agents, QR1-502, Vaccinology, Viral Matrix Proteins, structural vaccinology, Mice, Viral Envelope Proteins, vaccine, respiratory viruses, Viruses, computational protein design, Animals, Humans, Computer Simulation, Respiratory Tract Infections, glycoproteins
Clinical Trials as Topic, rational design, Viral Vaccines, Review, Microbiology, Antiviral Agents, QR1-502, Vaccinology, Viral Matrix Proteins, structural vaccinology, Mice, Viral Envelope Proteins, vaccine, respiratory viruses, Viruses, computational protein design, Animals, Humans, Computer Simulation, Respiratory Tract Infections, glycoproteins
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