Spindle pole body duplication: a model for centrosome duplication?
Authors: I R, Adams; J V, Kilmartin;
pmid: 10884685
Spindle pole body duplication: a model for centrosome duplication?
Abstract
The yeast spindle pole body (SPB) is the functional equivalent of the centrosome and forms the two poles of the mitotic spindle. Before mitosis, both SPBs and centrosomes are present as single copies and must be duplicated to form the bipolar spindle. SPB components have been identified using a combination of biochemistry and genetics, and their role during SPB duplication has been analysed using temperature-sensitive mutants. In this article, we describe structural aspects of SPB duplication and their possible relationship to centrosome duplication.
Related Organizations
- MRC Laboratory of Molecular Biology United Kingdom
- Medical Research Council United Kingdom
Keywords
Centrosome, Mitosis, Saccharomyces cerevisiae, Spindle Apparatus
Centrosome, Mitosis, Saccharomyces cerevisiae, Spindle Apparatus
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citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
107
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