Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation
Copyright policy )Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation
Key PointsThree or more mismatches at the Low Expression Loci may adversely affect clinical outcome after 7/8 matched transplantation. Match grade at the Low Expression HLA Loci may be considered to select 7/8 donors with potentially lower posttransplant risks.
- Moffitt Cancer Center United States
- The University of Texas System United States
- Stanford University United States
- Case Western Reserve University United States
- University of Minnesota Medical Center United States
Adult, Graft Rejection, Male, HLA-DP Antigens, Incidence, HLA-DR beta-Chains, Hematopoietic Stem Cell Transplantation, Kaplan-Meier Estimate, Middle Aged, Tissue Donors, HLA-DRB5 Chains, Young Adult, Risk Factors, HLA-DQ Antigens, Histocompatibility, Humans, Female, HLA-DRB3 Chains, HLA-DRB4 Chains
Adult, Graft Rejection, Male, HLA-DP Antigens, Incidence, HLA-DR beta-Chains, Hematopoietic Stem Cell Transplantation, Kaplan-Meier Estimate, Middle Aged, Tissue Donors, HLA-DRB5 Chains, Young Adult, Risk Factors, HLA-DQ Antigens, Histocompatibility, Humans, Female, HLA-DRB3 Chains, HLA-DRB4 Chains
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