Erythrocytosis caused by erythropoietin-producing thymic carcinoma

Name: Erythrocytosis caused by erythropoietin-producing thymic carcinoma
Keywords: Aged, 80 and over, Male, Time Factors, Thymoma, Paraneoplastic Syndromes, Biopsy, Fine-Needle, Polycythemia, Thymus Neoplasms, Thymectomy, Immunohistochemistry

descriptionPublicationkeyboard_double_arrow_right Article 24 Feb 2010 English Publisher:Springer Science and Business Media LLCJournal:International Journal of Clinical Oncology, volume 15, pages 220-223 (issn: 1341-9625, eissn: 1437-7772,

Authors: Wataru, Munakata; Kazuteru, Ohashi; Koji, Sakaguchi; Hirotoshi, Horio; Tsunekazu, Hishima; Hideki, Akiyama; Hisashi, Sakamaki;

doi: 10.1007/s10147-010-0029-x

pmid: 20179983

Erythrocytosis caused by erythropoietin-producing thymic carcinoma

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Abstract

We describe the first reported case, in an 82-year-old man, of erythrocytosis caused by an erythropoietin (EPO)-producing thymic carcinoma. The patient underwent computed tomography-guided fine-needle aspiration of a 6-cm anterior mediastinal mass, and histological findings revealed thymic squamous cell carcinoma. The existence of EPO was confirmed immunohistochemically using the tumor tissue. Postoperative clinical improvement of erythrocytosis and the decline of EPO suggest a paraneoplastic nature of erythrocytosis as seen in this patient.

Related Organizations

Tokyo Metropolitan Komagome Hospital
Japan

Keywords

Aged, 80 and over, Male, Time Factors, Thymoma, Paraneoplastic Syndromes, Biopsy, Fine-Needle, Polycythemia, Thymus Neoplasms, Thymectomy, Immunohistochemistry, Treatment Outcome, Phlebotomy, Carcinoma, Squamous Cell, Humans, Tomography, X-Ray Computed, Erythropoietin

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