FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets
FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets
Key PointsThe F-BAR protein PACSIN2 associates with the initiating demarcation membrane system in megakaryocytes. FlnA binding to the PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes, platelets, and in vitro.
- University of Toronto Canada
- Boston College United States
- Universtity of Cologne Germany
- Harvard Medical School United States
- Brigham and Women's Hospital United States
Blood Platelets, PACSIN2, Filamins, Cell Membrane, Mice, Transgenic, Mice, Inbred C57BL, Mice, HEK293 Cells, megakaryocytes, megakaryocytes, PACSIN2, filamin A, Animals, Humans, filamin A, Protein Interaction Domains and Motifs, Pseudopodia, Megakaryocytes, Cells, Cultured, Adaptor Proteins, Signal Transducing, Protein Binding
Blood Platelets, PACSIN2, Filamins, Cell Membrane, Mice, Transgenic, Mice, Inbred C57BL, Mice, HEK293 Cells, megakaryocytes, megakaryocytes, PACSIN2, filamin A, Animals, Humans, filamin A, Protein Interaction Domains and Motifs, Pseudopodia, Megakaryocytes, Cells, Cultured, Adaptor Proteins, Signal Transducing, Protein Binding
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