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Keeping RNA and DNA Apart during Transcription

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2003 English Publisher:Elsevier BVJournal:Molecular Cell, volume 12, pages 538-539 (issn: 1097-2765, Copyright policy )
Authors: Svejstrup, Jesper;

doi: 10.1016/s1097-2765(03)00354-x

pmid: 14527401

Keeping RNA and DNA Apart during Transcription

Abstract

Abstract In this issue of Molecular Cell , Huertas and Aguilera provide compelling evidence that the THO/TREX complex plays an important role in preventing RNA:DNA hybrids from forming during transcript elongation, thereby allowing efficient transcription of long genes and suppressing unwanted DNA recombination.

Related Organizations
Keywords

Eukaryotic Cells, Saccharomyces cerevisiae Proteins, Transcription, Genetic, Macromolecular Substances, Nucleic Acid Hybridization, RNA, Cell Biology, DNA, Molecular Biology, Transcription Factors

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
50
Top 10%
Top 10%
Top 10%
hybrid