Mapping the gene for LTW-4, a 26,000 molecular weight major protein of mouse liver and kidney
Copyright policy )Mapping the gene for LTW-4, a 26,000 molecular weight major protein of mouse liver and kidney
The polypeptide LTW-4 has previously been shown by 2D electrophoresis to be a major soluble protein of mouse liver. We now show that it is a major soluble polypeptide of mouse kidney. The Ltw-4 locus has been mapped on Chromosome 1 using the BXD, AKXL and BXH recombinant inbred strains. The gene order is Dip-1 Rnr - (Sas-1, ald) - Ltw-4 - Mls. The map distance between (Dip-1, Rnr) and Ltw-4 is estimated to be 12.2 +/- 4.2 cM, between Sas-1 and Ltw-4 5.4 +/- 2.6, between ald and Ltw-4 7.1 +/- 4.6 cM, and between Ltw-4 and Mls 4.3 +/- 2.0 cM. The strain distribution pattern of Ltw-4 is reported for the SWXL recombinant inbred strains and for a large number of inbred strains of mice.
- Roswell Park Cancer Institute United States
Recombination, Genetic, Chromosome Mapping, Proteins, Mice, Inbred Strains, Kidney, Molecular Weight, Mice, Genes, Liver, Animals, Crosses, Genetic
Recombination, Genetic, Chromosome Mapping, Proteins, Mice, Inbred Strains, Kidney, Molecular Weight, Mice, Genes, Liver, Animals, Crosses, Genetic
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