A novel glucokinase gene mutation and its effect on glycemic/C-peptide fluctuations in a patient with maturity-onset diabetes of the young type 2
Copyright policy )A novel glucokinase gene mutation and its effect on glycemic/C-peptide fluctuations in a patient with maturity-onset diabetes of the young type 2
Maturity-onset diabetes of the young (MODY) is a group of disorders accounting for 2-5% of diabetes; MODY2 is caused by inactivating GCK mutations. We report a case of MODY2 caused by a novel GCK mutation and demonstrate differential glycemic/C-peptide responses to treatment with insulin, no medication, and an oral sulfonylurea.
- University of California Davis Medical Center United States
- University of California, Davis United States
Blood Glucose, Male, Adolescent, C-Peptide, Glucose Tolerance Test, Sulfonylurea Compounds, Diabetes Mellitus, Type 2, Area Under Curve, Child, Preschool, Glucokinase, Mutation, Humans, Hypoglycemic Agents, Genetic Predisposition to Disease
Blood Glucose, Male, Adolescent, C-Peptide, Glucose Tolerance Test, Sulfonylurea Compounds, Diabetes Mellitus, Type 2, Area Under Curve, Child, Preschool, Glucokinase, Mutation, Humans, Hypoglycemic Agents, Genetic Predisposition to Disease
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