How T cells trigger the dissociation of the endothelial receptor phosphatase VE-PTP from VE-cadherin
Copyright policy )How T cells trigger the dissociation of the endothelial receptor phosphatase VE-PTP from VE-cadherin
Key PointsThe endothelial leukocyte receptor VCAM-1 triggers opening of endothelial junctions via dissociation of VE-PTP from VE-cadherin. VCAM-1 and VEGF signaling use a similar signaling pathway to trigger the dissociation of VE-PTP from VE-cadherin.
- Max Planck Society Germany
- Max Planck Institute for Molecular Biomedicine Germany
Mice, Antigens, CD, T-Lymphocytes, Immunoblotting, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Cell Adhesion, Transendothelial and Transepithelial Migration, Animals, Endothelial Cells, Immunoprecipitation, Vascular Cell Adhesion Molecule-1, Cadherins, Signal Transduction
Mice, Antigens, CD, T-Lymphocytes, Immunoblotting, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Cell Adhesion, Transendothelial and Transepithelial Migration, Animals, Endothelial Cells, Immunoprecipitation, Vascular Cell Adhesion Molecule-1, Cadherins, Signal Transduction
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