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Science Signaling
Article
Data sources: UnpayWall
Science Signaling
Article . 2009 . Peer-reviewed
Data sources: Crossref
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TRPM2 Functions as a Lysosomal Ca2+-Release Channel in β Cells

Authors: Lange, Ingo; Yamamoto, Shinichiro; Partida-Sanchez, Santiago; Mori, Yasuo; Fleig, Andrea; Penner, Reinhold;

TRPM2 Functions as a Lysosomal Ca2+-Release Channel in β Cells

Abstract

TRPM2-mediated Ca2+release from lysosomal stores contributes to pancreatic β cell death in response to oxidative stress.

Keywords

Mice, Knockout, Adenosine Diphosphate Ribose, Membrane Glycoproteins, Microscopy, Confocal, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Apoptosis, Hydrogen Peroxide, ADP-ribosyl Cyclase 1, Cell Line, Membrane Potentials, Mice, Inbred C57BL, Mice, Cell Line, Tumor, Insulin-Secreting Cells, Animals, Humans, Calcium, Lysosomes, Cells, Cultured

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    275
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
275
Top 1%
Top 10%
Top 1%
bronze