Age-related Auditory Brainstem Response (ABR) Threshold Changes in the Dancer Mouse Mutant
pmid: 3207006
Age-related Auditory Brainstem Response (ABR) Threshold Changes in the Dancer Mouse Mutant
An age-related analysis of auditory brainstem response (ABR) thresholds in 42 heterozygotic dancer mouse mutants (1-13 months old) showed an impairment of ABR thresholds with increasing age, though individual threshold curves could vary considerably. As compared with normal CBA/CBA mice, a progressive deterioration of ABR thresholds occurred from the 2nd postnatal month onwards. The dancer mutant has an inner ear with a morphogenetic type of defect, caused by a semidominant gene which is located in chromosome 19.
- Umeå University Sweden
- University Hospital of Umeå Sweden
Aging, Mice, Mice, Neurologic Mutants, Evoked Potentials, Auditory, Mice, Inbred CBA, Animals, Auditory Threshold, Rabbits, Deafness, Brain Stem, Genes, Dominant
Aging, Mice, Mice, Neurologic Mutants, Evoked Potentials, Auditory, Mice, Inbred CBA, Animals, Auditory Threshold, Rabbits, Deafness, Brain Stem, Genes, Dominant
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