Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast
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Catherine M. Moore; Jigang Wang; Qingsong Lin; Pedro Ferreira; Mitchell A. Avery; Khaled Elokely; Henry M. Staines; +1 Authors
Catherine M. Moore; Jigang Wang; Qingsong Lin; Pedro Ferreira; Mitchell A. Avery; Khaled Elokely; Henry M. Staines; Sanjeev Krishna;
Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast
Treatment failures with artemisinin combination therapies (ACTs) threaten global efforts to eradicate malaria. They highlight the importance of identifying drug targets and new inhibitors and of studying how existing antimalarial classes work.
- National University of Singapore Singapore
- Mississippi Institutions of Higher Learning United States
- St George's, University of London United Kingdom
- Nationl University of Singapore Singapore
- University of London United Kingdom
Mammals, Plasmodium falciparum, Drug Resistance, Calcium-Transporting ATPases, Saccharomyces cerevisiae, Artemisinins, Antimalarials, Animals, Malaria, Falciparum, Mechanisms of Action: Physiological Effects
Mammals, Plasmodium falciparum, Drug Resistance, Calcium-Transporting ATPases, Saccharomyces cerevisiae, Artemisinins, Antimalarials, Animals, Malaria, Falciparum, Mechanisms of Action: Physiological Effects
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).5 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 5
Top 10%
Average
Top 10%
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