A Bispecific Antibody Targeting RBD and S2 Potently Neutralizes SARS-CoV-2 Omicron and Other Variants of Concern
A Bispecific Antibody Targeting RBD and S2 Potently Neutralizes SARS-CoV-2 Omicron and Other Variants of Concern
The new, highly contagious SARS-CoV-2 Omicron variant caused substantial breakthrough infections and has become the dominant strain in countries across the world. Omicron variants usually bear high mutations in the spike protein and exhibit considerable escape of most potent neutralization monoclonal antibodies and reduced efficacy of current COVID-19 vaccines.
- China Agricultural University China (People's Republic of)
- Third Military Medical University China (People's Republic of)
- Chinese Academy of Medical Sciences & Peking Union Medical College China (People's Republic of)
- Southern Medical University China (People's Republic of)
- Xinqiao Hospital China (People's Republic of)
SARS-CoV-2, Antibodies, Monoclonal, Antibodies, Viral, Antibodies, Neutralizing, COVID-19 Drug Treatment, Epitopes, Neutralization Tests, Vaccines and Antiviral Agents, Antibodies, Bispecific, Spike Glycoprotein, Coronavirus, Humans
SARS-CoV-2, Antibodies, Monoclonal, Antibodies, Viral, Antibodies, Neutralizing, COVID-19 Drug Treatment, Epitopes, Neutralization Tests, Vaccines and Antiviral Agents, Antibodies, Bispecific, Spike Glycoprotein, Coronavirus, Humans
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