Sequence and Chromosomal Location of a Human Homologue of LRPR1, an FSH Primary Response Gene
Copyright policy )Sequence and Chromosomal Location of a Human Homologue of LRPR1, an FSH Primary Response Gene
The rat gene Leucine-Rich Primary Response Gene-1 (LRPR1) has been proposed to encode a protein involved in the response of gonadal tissues to follicle-stimulating hormone. We have characterized a human transcript that probably encodes the orthologue of the rat protein, exhibiting 72% identity at the amino acid level. The gene from which the transcript is derived maps to human chromosomal region Xq22 and therefore becomes a potential candidate for human X-linked disorders of gonadal development.
- Addenbrooke's Hospital United Kingdom
- Cambridge University Hospitals NHS Foundation Trust United Kingdom
DNA-Binding Proteins, Leucine Zippers, Sequence Homology, Amino Acid, Molecular Sequence Data, Animals, Chromosome Mapping, Humans, Amino Acid Sequence, Follicle Stimulating Hormone, Rats
DNA-Binding Proteins, Leucine Zippers, Sequence Homology, Amino Acid, Molecular Sequence Data, Animals, Chromosome Mapping, Humans, Amino Acid Sequence, Follicle Stimulating Hormone, Rats
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