Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells
Authors: Ranjit K. Sahu; Sandhya Xavier; Daniel Chauss; Luopin Wang; Claude Chew; Ronald Taylor; William B. Stallcup; +5 Authors
Ranjit K. Sahu; Sandhya Xavier; Daniel Chauss; Luopin Wang; Claude Chew; Ronald Taylor; William B. Stallcup; Jennie Z. Ma; Majid Kazemian; Behdad Afzali; Jörg Köhl; Didier Portilla;
Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells
Abstract
This study used novel green fluorescent protein C5a receptor 1 floxed mice and the model of folic acid-mediated kidney fibrosis to demonstrate the pathogenic role of increased expression of this complement receptor on macrophages.
Related Organizations
- University of Virginia United States
- National Institute of Health Pakistan
- Cincinnati Children's Hospital Medical Center United States
- Purdue University West Lafayette United States
- National Institutes of Health United States
Keywords
Mice, Knockout, Green Fluorescent Proteins, Kidney, Fibrosis, Cicatrix, Mice, Folic Acid, Animals, Myeloid Cells, Receptors, Platelet-Derived Growth Factor, Receptor, Anaphylatoxin C5a
Mice, Knockout, Green Fluorescent Proteins, Kidney, Fibrosis, Cicatrix, Mice, Folic Acid, Animals, Myeloid Cells, Receptors, Platelet-Derived Growth Factor, Receptor, Anaphylatoxin C5a
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
12
Top 10%
Average
Top 10%
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