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Lipids in Health and Disease
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Lipids in Health and Disease
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Lipids in Health and Disease
Article . 2010
Data sources: DOAJ
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The association between blood glucose and oxidized lipoprotein(a) in healthy young women

Authors: Yamada Toshiyuki; Uurtuya Shuumarjav; Yamada Shingo; Kotani Kazuhiko; Taniguchi Nobuyuki; Sakurabayashi Ikunosuke;

The association between blood glucose and oxidized lipoprotein(a) in healthy young women

Abstract

Oxidized lipoproteins play important roles in the atherosclerotic processes. Oxidized lipoprotein(a) (oxLp(a)) may be more potent in atherosclerotic pathophysiology than native Lp(a), a cardiovascular disease-relevant lipoprotein. Increased blood glucose concentrations can induce oxidative modification of lipoproteins. The aim of this study was to investigate the association between circulating oxLp(a) and cardiometabolic variables including blood glucose in healthy volunteers within the normal range of blood glucose.Several cardiometabolic variables and serum oxLp(a) (using an ELISA system) were measured among 70 healthy females (mean age, 22 years).Lp(a) and glucose were significantly and positively correlated with oxLp(a) in simple correlation test. Furthermore, a multiple linear regression analysis showed oxLp(a) to have a weakly, but significantly positive and independent correlation with only blood glucose (β = 0.269, P < 0.05).These results suggest that increased glucose may enhance the oxidization of Lp(a) even at normal glucose levels.

Keywords

Adult, Blood Glucose, RC620-627, Adolescent, Lipoproteins, Statistics as Topic, Blood Pressure, Apoprotein(a), Severity of Illness Index, Body Mass Index, Young Adult, Risk Factors, Short Paper, Humans, Nutritional diseases. Deficiency diseases, Atherosclerosis, Lipids, Early Diagnosis, Cardiovascular Diseases, Female, Oxidation-Reduction, Lipoprotein(a)

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Average
Average
Top 10%
Green
gold