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Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling

Authors: Jan M, Herter; Jan, Rossaint; Helena, Block; Heidi, Welch; Alexander, Zarbock;

Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling

Abstract

Key Points P-Rex1 is involved in E-selectin-mediated slow leukocyte rolling. P-Rex1 mediates Mac-1-dependent intravascular crawling.

Keywords

Integrins, Macrophage-1 Antigen, HL-60 Cells, Mice, Transgenic, Acute Kidney Injury, Intercellular Adhesion Molecule-1, Lymphocyte Function-Associated Antigen-1, Mice, Inbred C57BL, Chemotaxis, Leukocyte, Mice, Neutrophil Infiltration, Reperfusion Injury, Leukocytes, Animals, Blood Vessels, Guanine Nucleotide Exchange Factors, Humans, Leukocyte Rolling, E-Selectin, Cells, Cultured

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Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
63
Top 10%
Top 10%
Top 10%