While studying Anthurium sect. Pachyneurium from Brazil, a new species Anthurium mayoanum was discovered in Floresta de Igapó from Pará State. The species is described and illustrated. The species presents a set of characteristics that are for sect. Pachyneurium, particularly the atypical base of leaf blade and the color of spadix. We have compared this new species with other related taxa of section Pachyneurium and have provided commentary on geographical distribution, conservation status, ecology and phenology.