Esterase-8 (Es-8): Characterization, polymorphism, and linkage of an erythrocyte esterase locus on chromosome 7 of Mus musculus
Copyright policy )Esterase-8 (Es-8): Characterization, polymorphism, and linkage of an erythrocyte esterase locus on chromosome 7 of Mus musculus
An electrophoretic polymorphism of an erythrocyte esterase, esterase-8, specific for the substrates α- and β-naphthyl acetate has been observed in the Asian house mouse, Mus musculus castaneus. M. m. castaneus is interfertile with inbred strains of mice, and F1 hybrids (C57BL/6J × castaneus)F1 and (SWR/J × castaneus)F1 show a double-banded phenotype similar to a mixture of parental forms. This pattern suggests codominant expression of a structural gene difference. In backcrosses, ES-8 segregated as a single autosomal gene, designated Es-8, linked to Gpi-1 on chromosome 7. A gene order of Es-8, Gpi-1, c, Mod-2, and Hbb was determined from a series of crosses.
- Yale University United States
- Roswell Park Cancer Institute United States
- Jackson Laboratory United States
Male, LG, Erythrocytes, HRS, PH, Genetic Linkage, Hbd, Electrophoresis, Starch Gel, C57BL/6, RIII (R3A), LP, SEC/1, Biochemistry, DE, Mice, Gene Frequency, Metabolism:, Hb*s, C58, DW, PLB), Recombination, Genetic, C3H/HE, C57L, SEA, Esterases, Chromosome Mapping, P, 129, mitochondrial, CE, ROP, Organs:, Genes: c - Albino, Phenotype, Organ Specificity, Female, CBA, Linkage:, BDP, DBA/2 (212), 570, Heterozygote, BUB, Genotype, Hbb - Hemoblobin-beta-chain=Hb*b, Mdh-2 - Malic dehydrogenase-2, SJL, 610, Mod-2 - Malic enzyme, Mice, Inbred Strains, Chromosomes, PL (PLA, Origin:, Animals, RF (W), AKR, SIMPSON, Es-8 - Esterase-8, Crosses, Genetic, SWR, Unknown:, Polymorphism, Genetic, IC, C57BR/CD, L (P), MA (MARSH), Gpi-1 - Alucose phosphate isomerase-1 (all), AU, Hybridization, Genetic, Strains: A/HE, Hereditary Factors:
Male, LG, Erythrocytes, HRS, PH, Genetic Linkage, Hbd, Electrophoresis, Starch Gel, C57BL/6, RIII (R3A), LP, SEC/1, Biochemistry, DE, Mice, Gene Frequency, Metabolism:, Hb*s, C58, DW, PLB), Recombination, Genetic, C3H/HE, C57L, SEA, Esterases, Chromosome Mapping, P, 129, mitochondrial, CE, ROP, Organs:, Genes: c - Albino, Phenotype, Organ Specificity, Female, CBA, Linkage:, BDP, DBA/2 (212), 570, Heterozygote, BUB, Genotype, Hbb - Hemoblobin-beta-chain=Hb*b, Mdh-2 - Malic dehydrogenase-2, SJL, 610, Mod-2 - Malic enzyme, Mice, Inbred Strains, Chromosomes, PL (PLA, Origin:, Animals, RF (W), AKR, SIMPSON, Es-8 - Esterase-8, Crosses, Genetic, SWR, Unknown:, Polymorphism, Genetic, IC, C57BR/CD, L (P), MA (MARSH), Gpi-1 - Alucose phosphate isomerase-1 (all), AU, Hybridization, Genetic, Strains: A/HE, Hereditary Factors:
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