α4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development
Copyright policy )α4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development
By RNA in situ hybridization and immunohistochemical analyses of early stage mouse embryos, we find that alpha 4 integrin gene is expressed in migratory cranial neural crest cells originating from the presumptive forebrain, midbrain, and rhombomeres 1 and 2 of the presumptive hindbrain. alpha 4 is also expressed in epicardial progenitor cells in the septum transversum that migrate to the heart.
- Johns Hopkins University School of Medicine United States
- Johns Hopkins Medicine United States
Embryology, Time Factors, Integrin alpha4, Stem Cells, Embryo, Mammalian, Immunohistochemistry, Rhombencephalon, Mice, Prosencephalon, Antigens, CD, Mesencephalon, Neural Crest, Animals, RNA, Pericardium, In Situ Hybridization, Developmental Biology
Embryology, Time Factors, Integrin alpha4, Stem Cells, Embryo, Mammalian, Immunohistochemistry, Rhombencephalon, Mice, Prosencephalon, Antigens, CD, Mesencephalon, Neural Crest, Animals, RNA, Pericardium, In Situ Hybridization, Developmental Biology
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