Identification of a novel HLA‐DPB1 allele, DPB1*02014, by sequence‐based typing
Copyright policy )Identification of a novel HLA‐DPB1 allele, DPB1*02014, by sequence‐based typing
Abstract: In this report we describe the identification of a novel DPB1 allele, DPB1*02014, found in an Italian Caucasian individual.The new allele was detected during routine HLA sequence‐based typing (SBT) for an individual undergoing bone marrow transplantation. DPB1*02014 was identical to DPB1*02012 except for a single nucleotide substitution in codon 72 (GTG→GTT). This nucleotide change represents a synonimous mutation, as both triplets code for a valine.This new allele has been submitted to GenBank and assigned the accession number AF326565. The WHO Nomenclature Committee has officially assigned the name DPB1*02014.
HLA-DP Antigens, Base Sequence, Histocompatibility Testing, Genes, MHC Class II, Molecular Sequence Data, Polymerase Chain Reaction, White People, Italy, Humans, Sequence Alignment, HLA-DP beta-Chains, Bone Marrow Transplantation, DNA Primers
HLA-DP Antigens, Base Sequence, Histocompatibility Testing, Genes, MHC Class II, Molecular Sequence Data, Polymerase Chain Reaction, White People, Italy, Humans, Sequence Alignment, HLA-DP beta-Chains, Bone Marrow Transplantation, DNA Primers
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