Beyond the Closed Suture in Apert Syndrome Mouse Models: Evidence of Primary Effects of FGFR2 Signaling on Facial Shape at Birth
Copyright policy )Beyond the Closed Suture in Apert Syndrome Mouse Models: Evidence of Primary Effects of FGFR2 Signaling on Facial Shape at Birth
AbstractSuperimposed 3D visualization of the skull and head of mutant and non‐mutant littermates of the FGFR2 P253R mouse model at birth (P0). Lateral views of skeletal bone reconstructed from μCT isosurfaces are displayed. Skin surfaces are visualized from volume renderings; red (top left): Fgfr2+/+ non‐mutant littermate of the P253R model; and green (bottom right): Fgfr2+/P253R mutant littermate. From Martínez‐Abadías et al., Developmental Dynamics 239:3058–3071, 2010.
- University of Missouri Health System United States
- University of Missouri United States
- Icahn School of Medicine at Mount Sinai United States
- Pennsylvania State University United States
Craniosynostoses, Disease Models, Animal, Mice, Animals, Newborn, Skull, Animals, Mice, Transgenic, Acrocephalosyndactylia, Receptor, Fibroblast Growth Factor, Type 2
Craniosynostoses, Disease Models, Animal, Mice, Animals, Newborn, Skull, Animals, Mice, Transgenic, Acrocephalosyndactylia, Receptor, Fibroblast Growth Factor, Type 2
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