Leucapheresis for management of retinopathy in chronic myeloid leukaemia
Copyright policy )Leucapheresis for management of retinopathy in chronic myeloid leukaemia
Chronic myeloid leukaemia is a myeloproliferative neoplasm characterised by granulocytic hyperplasia in the bone marrow and the presence of a specific cytogenetic abnormality known as Philadelphia chromosome with fusion of breakpoint cluster region (BCR) and ableson (ABL) genes. Retinopathy is a rare sight-threatening complication of chronic myeloid leukaemia, which occurs due to leucostasis in retinal blood vessels. We report a case of a patient who presented with visual impairment due to leucostasis, who was successfully managed by leucapheresis along with BCR-ABL tyrosine kinase inhibitor.
- Launceston General Hospital Australia
Male, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Dasatinib, Vision Disorders, Humans, Philadelphia Chromosome, Leukapheresis, Middle Aged, Protein Kinase Inhibitors
Male, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Dasatinib, Vision Disorders, Humans, Philadelphia Chromosome, Leukapheresis, Middle Aged, Protein Kinase Inhibitors
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