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De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 03 Dec 2021 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 7 (eissn: 2375-2548, Copyright policy )Funded by:NHMRC | Peripheral Membrane Prote..., NIH | NCCAT: National Center fo..., ARC | Discovery Projects - Gran... +6 projects
Authors: Kai-En Chen; Qian Guo; Timothy A. Hill; Yi Cui; Amy K. Kendall; Zhe Yang; Ryan J. Hall; +16 Authors

doi: 10.1126/sciadv.abg4007

pmid: 34851660

pmc: PMC8635440

handle: 11343/296278

De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

Abstract

Novel macrocyclic peptides are found that bind and modulate the function of the retromer membrane trafficking complex.

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Keywords

610, 540, Neuroscience

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 24
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
24
Top 10%
Top 10%
Top 10%
Green
gold
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