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FEBS Letters
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FEBS Letters
Article . 2005 . Peer-reviewed
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FEBS Letters
Article . 2005
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RNA silencing in Drosophila

Authors: Kavi, Harsh H.; Fernandez, Harvey R.; Xie, Weiwu; Birchler, James A.;
Abstract

Knowledge of the role of RNA in affecting gene expression has expanded in the past several years. Small RNAs serve as homology guides to target messenger RNAs for destruction at the post‐transcriptional level in the experimental technique known as RNA interference and in the silencing of some transgenes. These small RNAs are also involved in sequence‐specific targeting of chromatin modifications for transcriptional silencing of transgenes, transposable elements, heterochromatin and some cases of Polycomb‐mediated gene silencing. RNA silencing processes in Drosophila are described.

Related Organizations
Keywords

RNA editing, DNA Repair, Transcription, Genetic, Cosuppression, Models, Biological, Heterochromatin, Animals, Gene Silencing, RNA, Messenger, Transgenes, RNA, Small Interfering, Models, Genetic, Transgene silencing, DNA, Chromatin, Drosophila melanogaster, Gene Expression Regulation, RNAi, DNA Transposable Elements, RNA, RNA Interference, RNA Editing, Transposons, Protein Processing, Post-Translational

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    62
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
62
Top 10%
Top 10%
Top 1%
bronze