Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer-3
Authors: Heinonen, Henna; Nieminen, Anni; Saarela, Matti; Kallioniemi, Anne; Klefström, Juha; Hautaniemi, Sampsa; Monni, Outi;
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer-3
Abstract
R 24 hours and the protein expression of eIF4G1 was detected by Western immunoblotting. The plus (+) sign indicates the inhibitor-treated sample and the minus (-) sign the non-treated sample. A) Rapamycin and B) Ly294002 downregulated eIF4G1 expression at protein level in BT-474 and SK-BR-3 cells, respectively. Beta-actin was used as a loading control.Copyright information:Taken from "Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer"http://www.biomedcentral.com/1471-2164/9/348BMC Genomics 2008;9():348-348.Published online 24 Jul 2008PMCID:PMC2496917.
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