Keeping mRNPs in check during assembly and nuclear export
Copyright policy )Keeping mRNPs in check during assembly and nuclear export
The cell nucleus is an intricate organelle that coordinates multiple activities that are associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic information and the machineries that control the production of mature and export-competent messenger ribonucleoproteins (mRNPs), a multistep process that is regulated in a spatial and temporal manner. Recent studies suggest that post-translational modifications play a part in coordinating the co-transcriptional assembly, remodelling and export of mRNP complexes through nuclear pores, adding a new level of regulation to the process of gene expression.
- University of Geneva Switzerland
Cell Nucleus, DNA Replication, 570, Nucleocytoplasmic Transport Proteins, Ribonucleoproteins/metabolism, Active Transport, Cell Nucleus, Gene Expression, Saccharomyces cerevisiae, Nuclear Pore/metabolism, Gene Expression Regulation, Nuclear Matrix-Associated Proteins, Ribonucleoproteins, Nucleocytoplasmic Transport Proteins/metabolism, Cell Nucleus/metabolism, Nuclear Matrix-Associated Proteins/metabolism, Nuclear Pore, Humans, RNA Polymerase II, Protein Processing, Post-Translational, ddc: ddc:570
Cell Nucleus, DNA Replication, 570, Nucleocytoplasmic Transport Proteins, Ribonucleoproteins/metabolism, Active Transport, Cell Nucleus, Gene Expression, Saccharomyces cerevisiae, Nuclear Pore/metabolism, Gene Expression Regulation, Nuclear Matrix-Associated Proteins, Ribonucleoproteins, Nucleocytoplasmic Transport Proteins/metabolism, Cell Nucleus/metabolism, Nuclear Matrix-Associated Proteins/metabolism, Nuclear Pore, Humans, RNA Polymerase II, Protein Processing, Post-Translational, ddc: ddc:570
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