Single-Nucleotide Polymorphism in the fadD28 Gene as a Genetic Marker for East Asia Lineage Mycobacterium tuberculosis
Copyright policy )Single-Nucleotide Polymorphism in the fadD28 Gene as a Genetic Marker for East Asia Lineage Mycobacterium tuberculosis
ABSTRACT Mycobacterium tuberculosis isolates with a region of difference 105 (RD105) deletion, mainly Beijing family spoligotypes, were phylogenetically grouped into the East Asia lineage. We identified a single nucleotide polymorphism in codon 507, ATC to ATT, of the fadD28 gene as a robust marker and developed a rapid assay for East Asia lineage M. tuberculosis .
- Centers for Disease Control and Prevention United States
DNA, Bacterial, Bacteriological Techniques, Molecular Epidemiology, Molecular Sequence Data, Mycobacterium tuberculosis, Sequence Analysis, DNA, Polymorphism, Single Nucleotide, Carbon-Sulfur Ligases, Cluster Analysis, Humans, Tuberculosis, Phylogeny
DNA, Bacterial, Bacteriological Techniques, Molecular Epidemiology, Molecular Sequence Data, Mycobacterium tuberculosis, Sequence Analysis, DNA, Polymorphism, Single Nucleotide, Carbon-Sulfur Ligases, Cluster Analysis, Humans, Tuberculosis, Phylogeny
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