Cell Polarity: Posterior Par-1 Prevents Proteolysis
pmid: 12176345
Cell Polarity: Posterior Par-1 Prevents Proteolysis
The Par-1 kinase is required for anterior-posterior axis formation in Drosophila. New work has identified the posterior determinant, Oskar, as a Par-1 substrate. Phosphorylation stabilises Oskar, revealing a novel mechanism controlling its asymmetric distribution.
- University of Cambridge United Kingdom
- Wellcome Trust United Kingdom
- Department of Genetics, University of Cambridge, UK United Kingdom
Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Hydrolysis, Cell Polarity, Protein Serine-Threonine Kinases, Animals, Drosophila Proteins, Drosophila, RNA, Messenger, Phosphorylation, Caenorhabditis elegans Proteins
Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Hydrolysis, Cell Polarity, Protein Serine-Threonine Kinases, Animals, Drosophila Proteins, Drosophila, RNA, Messenger, Phosphorylation, Caenorhabditis elegans Proteins
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