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Biology of Reproduction
Article . 2021 . Peer-reviewed
License: OUP Standard Publication Reuse
Data sources: Crossref
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Influence of SARS-CoV-2 during pregnancy: a placental view

Authors: Marcos Aurélio Santos, da Costa; Diana Babini Lapa, de Albuquerque Britto; Maria Eduarda, da Silva; Jennyfer Martins, de Carvalho; Maria Luísa Figueira, de Oliveira; José Anderson, da Silva Gomes; Fernanda das Chagas Angelo, Mendes Tenorio; +1 Authors

Influence of SARS-CoV-2 during pregnancy: a placental view

Abstract

Abstract Since the beginning of the current coronavirus outbreak (COVID-19), there has been great concern over a disease that has spread rapidly in several countries worldwide, with the result of several deaths, including deaths of pregnant women. Therefore, the aim of this study was to conduct a literature review on placental changes in infected pregnant women and/or asymptomatic carriers of COVID-19 during pregnancy, aiming at the possible vertical transmission. A systematic collection was carried out on the effects of that COVID-19 can cause directly and/or indirectly to pregnancy and the placenta in the following databases: Pubmed, Science Direct, Scielo, Lilacs, and Web of Science. For search, the following descriptors were used: placenta, pregnant woman, COVID-19, maternal–fetal. The results indicate transplacental transmission in some cases reviewed in many reports from this study. The presence of the virus was seen in the amniotic fluid, umbilical cord, and peripheral blood. Finally, pathological studies suggest that there are morphological changes related to infection in the placentas. We can conclude that, based on the researched material, there is little evidence of transplacental vertical viral transmission and its respective morphological changes related to viral infection in the placenta.

Keywords

Pregnancy, SARS-CoV-2, Placenta, COVID-19, Humans, Female, Pregnancy Complications, Infectious, Infectious Disease Transmission, Vertical

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
hybrid