Zinc is required for structural stability of the C‐terminus of archaeal translation initiation factor aIF2β
pmid: 12062427
Zinc is required for structural stability of the C‐terminus of archaeal translation initiation factor aIF2β
aIF2β is an archaeal homolog of eukaryotic translation factor eIF2β necessary for translation initiation and involved in recognition of the initiation codon. In the present study, we demonstrate for the first time zinc binding to the C2–C2 zinc finger at the C‐terminus of aIF2β. Nuclear magnetic resonance backbone assignments were also determined and the secondary structural elements identified.
Sequence Homology, Amino Acid, Archaeal Proteins, Molecular Sequence Data, Zinc Fingers, RNA binding, Euryarchaeota, Protein Structure, Secondary, Nuclear magnetic resonance, Zinc, aIF2β, Zinc finger, Secondary structure, Protein Biosynthesis, Translation initiation, Amino Acid Sequence
Sequence Homology, Amino Acid, Archaeal Proteins, Molecular Sequence Data, Zinc Fingers, RNA binding, Euryarchaeota, Protein Structure, Secondary, Nuclear magnetic resonance, Zinc, aIF2β, Zinc finger, Secondary structure, Protein Biosynthesis, Translation initiation, Amino Acid Sequence
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