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FEBS Letters
Article . 2002 . Peer-reviewed
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FEBS Letters
Article . 2002
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Zinc is required for structural stability of the C‐terminus of archaeal translation initiation factor aIF2β

Authors: Gutiérrez, Pablo; Coillet-Matillon, Stéphane; Arrowsmith, Cheryl; Gehring, Kalle;

Zinc is required for structural stability of the C‐terminus of archaeal translation initiation factor aIF2β

Abstract

aIF2β is an archaeal homolog of eukaryotic translation factor eIF2β necessary for translation initiation and involved in recognition of the initiation codon. In the present study, we demonstrate for the first time zinc binding to the C2–C2 zinc finger at the C‐terminus of aIF2β. Nuclear magnetic resonance backbone assignments were also determined and the secondary structural elements identified.

Keywords

Sequence Homology, Amino Acid, Archaeal Proteins, Molecular Sequence Data, Zinc Fingers, RNA binding, Euryarchaeota, Protein Structure, Secondary, Nuclear magnetic resonance, Zinc, aIF2β, Zinc finger, Secondary structure, Protein Biosynthesis, Translation initiation, Amino Acid Sequence

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    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
9
Average
Average
Average
bronze