Key Divisions in the Early Arabidopsis Embryo Require POL and PLL1 Phosphatases to Establish the Root Stem Cell Organizer and Vascular Axis
Copyright policy )Key Divisions in the Early Arabidopsis Embryo Require POL and PLL1 Phosphatases to Establish the Root Stem Cell Organizer and Vascular Axis
Arabidopsis development proceeds from three stem cell populations located at the shoot, flower, and root meristems. The relationship between the highly related shoot and flower stem cells and the very divergent root stem cells has been unclear. We show that the related phosphatases POL and PLL1 are required for all three stem cell populations. pol pll1 mutant embryos lack key asymmetric divisions that give rise to the root stem cell organizer and the central vascular axis. Instead, these cells divide in a superficially symmetric fashion in pol pll1 embryos, leading to a loss of embryonic and postembryonic root stem cells and vascular specification. We present data that show that POL/PLL1 drive root stem cell specification by promoting expression of the WUS homolog WOX5. We propose that POL and PLL1 are required for the proper divisions of shoot, flower, and root stem cell organizers, WUS/WOX5 gene expression, and stem cell maintenance.
- University of Michigan–Flint United States
- Yonsei University Korea (Republic of)
- University of Michigan–Ann Arbor United States
- UNIVERSITY OF MICHIGAN AT ANN ARBOR
- University of Michigan United States
Homeodomain Proteins, Arabidopsis Proteins, Stem Cells, Meristem, Arabidopsis, Gene Expression Regulation, Developmental, DEVBIO, Genes, Plant, Life sciences, STEMCELL, Models, Biological, Plant Roots, Biologie/Milieukunde (BIOL), Gene Expression Regulation, Plant, Mutation, Phosphoprotein Phosphatases, Developmental Biology
Homeodomain Proteins, Arabidopsis Proteins, Stem Cells, Meristem, Arabidopsis, Gene Expression Regulation, Developmental, DEVBIO, Genes, Plant, Life sciences, STEMCELL, Models, Biological, Plant Roots, Biologie/Milieukunde (BIOL), Gene Expression Regulation, Plant, Mutation, Phosphoprotein Phosphatases, Developmental Biology
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