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A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

Authors: Shuai Xia; Lei Yan; Wei Xu; Anurodh Shankar Agrawal; Abdullah Algaissi; Chien-Te K. Tseng; Qian Wang; +6 Authors

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

Abstract

EK1 is a broad-spectrum human coronavirus fusion inhibitor for combating infection of current and emerging coronaviruses.

Related Organizations
Keywords

Models, Molecular, Protein Conformation, Membrane Fusion, Cell Line, Coronavirus, Disease Models, Animal, Mice, Protein Domains, Solubility, Spike Glycoprotein, Coronavirus, Animals, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Coronavirus Infections, Peptides, Research Articles, Phylogeny, Viral Fusion Protein Inhibitors

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    431
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 0.1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 0.1%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
431
Top 0.1%
Top 1%
Top 0.1%
Green
gold