BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5′ UTR
Copyright policy )BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5′ UTR
BST2 is a potent antiviral protein that suppresses the release of several enveloped viruses, mainly by tethering the envelope of newly synthesized virions and restraining them on the surface of producer cells. In mammalian cells, there are numerous DNA elements replicating through reverse transcription, among which LINE-1 is the only retroelement that can replicate autonomously.
- First Hospital of Jilin University China (People's Republic of)
- Jilin University China (People's Republic of)
GPI-Linked Proteins, Genomic Instability, Immunity, Innate, Gene Delivery, HEK293 Cells, Long Interspersed Nucleotide Elements, Protein Domains, Antigens, CD, Mutation, Humans, 5' Untranslated Regions, Promoter Regions, Genetic
GPI-Linked Proteins, Genomic Instability, Immunity, Innate, Gene Delivery, HEK293 Cells, Long Interspersed Nucleotide Elements, Protein Domains, Antigens, CD, Mutation, Humans, 5' Untranslated Regions, Promoter Regions, Genetic
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