Recurrent epimutation ofSDHCin gastrointestinal stromal tumors
Authors: Zengfeng Wang; J. Keith Killian; Carly J Smith; Sosipatros Boikos; Su Young Kim; Holly S. Stevenson; Zhiming Yang; +15 Authors
Zengfeng Wang; J. Keith Killian; Carly J Smith; Sosipatros Boikos; Su Young Kim; Holly S. Stevenson; Zhiming Yang; William I. Smith; Paul S. Meltzer; Natalia Noyes; M. Scott Killian; Markku Miettinen; Jennifer Walling; Joshua J. Waterfall; Marbin Pineda; Yonghong Wang; C. Christopher Lau; Lee J. Helman; Parvathy Retnakumar; Robert L. Walker; Jerzy Lasota; Yuelin Jack Zhu;
Recurrent epimutation ofSDHCin gastrointestinal stromal tumors
Abstract
Methylation of theSDHgene explains the loss ofSDHgene expression in SDH wild-type gastrointestinal stromal tumors.
Related Organizations
- Suburban Hospital United States
- Center for Cancer Research United States
- National Heart Lung and Blood Institute United States
- Johns Hopkins Medicine United States
- National Cancer Institute United States
Keywords
Adult, Male, Adolescent, Gastrointestinal Stromal Tumors, Mosaicism, Membrane Proteins, DNA Methylation, Middle Aged, Enzyme Activation, Young Adult, Mutation, Humans, Female, Gene Silencing, Child, Promoter Regions, Genetic
Adult, Male, Adolescent, Gastrointestinal Stromal Tumors, Mosaicism, Membrane Proteins, DNA Methylation, Middle Aged, Enzyme Activation, Young Adult, Mutation, Humans, Female, Gene Silencing, Child, Promoter Regions, Genetic
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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