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Science Translational Medicine
Article . 2014 . Peer-reviewed
Data sources: Crossref
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Recurrent epimutation ofSDHCin gastrointestinal stromal tumors

Authors: Zengfeng Wang; J. Keith Killian; Carly J Smith; Sosipatros Boikos; Su Young Kim; Holly S. Stevenson; Zhiming Yang; +15 Authors

Recurrent epimutation ofSDHCin gastrointestinal stromal tumors

Abstract

Methylation of theSDHgene explains the loss ofSDHgene expression in SDH wild-type gastrointestinal stromal tumors.

Keywords

Adult, Male, Adolescent, Gastrointestinal Stromal Tumors, Mosaicism, Membrane Proteins, DNA Methylation, Middle Aged, Enzyme Activation, Young Adult, Mutation, Humans, Female, Gene Silencing, Child, Promoter Regions, Genetic

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    175
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
175
Top 1%
Top 10%
Top 1%
bronze