Histamine receptor 2 is a key influence in immune responses to intestinal histamine-secreting microbes
pmid: 24954261
Histamine receptor 2 is a key influence in immune responses to intestinal histamine-secreting microbes
Mucosal expression of histamine receptor 2 is critical for immunomodulatory responses to bacterial derived histamine. Histamine secreting microbes may be important intervention targets in patients with mucosal inflammatory disorders while the selection of enteric microbes for potential probiotic use needs to be conducted more in depth than is currently routinely performed.
- Swiss Institute of Allergy and Asthma Research
- University of Zurich Switzerland
- CK-CARE Switzerland
- ETH Zurich Switzerland
- Kantonsspital St. Gallen Switzerland
610 Medicine & health, Mice, Inbred Strains, Cell Line, Immunomodulation, Mice, 10183 Swiss Institute of Allergy and Asthma Research, Animals, Humans, Receptors, Histamine H2, Mice, Knockout, 2403 Immunology, Microbiota, Immunity, NF-kappa B, Famotidine, Coculture Techniques, Intestines, Lactobacillus, 10036 Medical Clinic, 2723 Immunology and Allergy, Cytokines, Histamine
610 Medicine & health, Mice, Inbred Strains, Cell Line, Immunomodulation, Mice, 10183 Swiss Institute of Allergy and Asthma Research, Animals, Humans, Receptors, Histamine H2, Mice, Knockout, 2403 Immunology, Microbiota, Immunity, NF-kappa B, Famotidine, Coculture Techniques, Intestines, Lactobacillus, 10036 Medical Clinic, 2723 Immunology and Allergy, Cytokines, Histamine
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