Spinsters, Synaptic Defects, and Amaurotic Idiocy
Copyright policy )Spinsters, Synaptic Defects, and Amaurotic Idiocy
In this issue of Neuron, Sweeney and Davis present a beautiful characterization of Drosophila mutants in a gene named spinster. The results indicate a function of the endocytic pathway in regulating transforming growth factor-beta (TGF-beta) signaling at the Drosophila motor synapse. This study provides important new information at an intersection of several disciplines, including membrane traffic, lipid organization, synaptic signaling, and neurodegenerative lysosomal storage disease.
- University of Arizona United States
Lysosomal Storage Diseases, Nervous System, Neuroscience(all), Neuromuscular Junction, Membrane Proteins, Synaptic Transmission, Endocytosis, Drosophila melanogaster, Transforming Growth Factor beta, Mutation, Animals, Drosophila Proteins, Humans, Signal Transduction
Lysosomal Storage Diseases, Nervous System, Neuroscience(all), Neuromuscular Junction, Membrane Proteins, Synaptic Transmission, Endocytosis, Drosophila melanogaster, Transforming Growth Factor beta, Mutation, Animals, Drosophila Proteins, Humans, Signal Transduction
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