Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1
Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1
Key amino acids in the chemokine XCL1 mediate its specificity for and activation of its receptor XCR1.
- KU Leuven Belgium
- Kindai University Japan
- Medical College of Wisconsin United States
- University of Copenhagen Denmark
- University of Copenhagen Denmark
3101 Biochemistry and cell biology, Protein Conformation, Molecular Dynamics Simulation, 0601 Biochemistry and Cell Biology, Chemokines, C, Receptors, G-Protein-Coupled, Radioligand Assay, Structure-Activity Relationship, HEK293 Cells, COS Cells, Chlorocebus aethiops, Animals, Humans, Amino Acids, Chemokines, Protein Binding, Signal Transduction
3101 Biochemistry and cell biology, Protein Conformation, Molecular Dynamics Simulation, 0601 Biochemistry and Cell Biology, Chemokines, C, Receptors, G-Protein-Coupled, Radioligand Assay, Structure-Activity Relationship, HEK293 Cells, COS Cells, Chlorocebus aethiops, Animals, Humans, Amino Acids, Chemokines, Protein Binding, Signal Transduction
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