The β crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5
Copyright policy )The β crystallin genes on human chromosome 22 define a new region of homology with mouse chromosome 5
The human beta crystallin genes CRYBB2, CRYBB2P1, CRYBB3, and CRYBA4 are located in 22q11.2. Using interspecific backcross analysis, we mapped the mouse homologues of CRYBB2, CRYBB3, and CRYBA4 (i.e., Crybb2, Crybb3, and Cryba4) to the central region of mouse chromosome 5. The homologue of human CRYBB2P1 is absent in mouse. These assignments define a new region of homology in human and mouse.
- University of Amsterdam Netherlands
- Amsterdam UMC Netherlands
Genetic Markers, Chromosomes, Human, Pair 22, Chromosome Mapping, Crystallins, Cataract, Mice, Inbred C57BL, Muridae, Mice, Species Specificity, Sequence Homology, Nucleic Acid, Animals, Humans, Hybridization, Genetic, Crosses, Genetic
Genetic Markers, Chromosomes, Human, Pair 22, Chromosome Mapping, Crystallins, Cataract, Mice, Inbred C57BL, Muridae, Mice, Species Specificity, Sequence Homology, Nucleic Acid, Animals, Humans, Hybridization, Genetic, Crosses, Genetic
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