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Muscle Differentiation: How Two Cells Become One

pmid: 11909553
Muscle Differentiation: How Two Cells Become One
A key feature of myogenesis is the fusion of myoblasts to form multinucleate myotubes. Recent work in Drosophila has uncovered a collection of genes that operate at different stages of this process. Some interactions between them have been described that begin to define links from outside the cell via the plasma membrane to the cytoskeleton. Future studies will establish the extent to which the molecular mechanisms of myoblast fusion are conserved between Drosophila and other animals, as found in other aspects of myogenesis.
- Cardiff University United Kingdom
- Cardiff University United Kingdom
Cytoplasm, Embryo, Nonmammalian, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Muscles, Cell Membrane, Gene Expression Regulation, Developmental, Membrane Proteins, Muscle Proteins, Cell Differentiation, Sodium Channels, Cell Fusion, Mesoderm, NAV1.8 Voltage-Gated Sodium Channel, Animals, Drosophila Proteins, Insect Proteins, Drosophila
Cytoplasm, Embryo, Nonmammalian, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Muscles, Cell Membrane, Gene Expression Regulation, Developmental, Membrane Proteins, Muscle Proteins, Cell Differentiation, Sodium Channels, Cell Fusion, Mesoderm, NAV1.8 Voltage-Gated Sodium Channel, Animals, Drosophila Proteins, Insect Proteins, Drosophila
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