Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
Copyright policy )Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
The products of six unidentified reading frames of human mitochondrial DNA are precipitated from a mitochondrial lysate by antibodies against highly purified native beef heart NADH-ubiquinone oxidoreductase (complex I). These products are enriched greatly in a human submitochondrial fraction enriched in NADH-Q1 and NADH-K3Fe(CN)6 oxidoreductase activities. We conclude that the six reading frames encode components of the respiratory-chain NADH dehydrogenase.
- California Institute of Technology United States
- University of California, San Diego United States
- University of Southampton United Kingdom
- Scripps Health United States
- University of California, San Diego United States
Macromolecular Substances, NADH Dehydrogenase, Intracellular Membranes, DNA, Mitochondrial, Molecular Weight, Genes, NAD(P)H Dehydrogenase (Quinone), Animals, Humans, Cattle, NADH, NADPH Oxidoreductases, Quinone Reductases, Cytochrome Reductases
Macromolecular Substances, NADH Dehydrogenase, Intracellular Membranes, DNA, Mitochondrial, Molecular Weight, Genes, NAD(P)H Dehydrogenase (Quinone), Animals, Humans, Cattle, NADH, NADPH Oxidoreductases, Quinone Reductases, Cytochrome Reductases
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