Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome
Copyright policy )Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome
Blocking a BMP signaling pathway may ameliorate neurological defects in patients with fragile X syndrome.
- University of California, Davis United States
- Massachusetts General Hospital United States
- University of California, San Francisco United States
- Vanderbilt University United States
- Harvard University United States
Cofilin 1, 570, Heterozygote, Intellectual and Developmental Disabilities (IDD), Knockout, Prefrontal Cortex, Crosses, Small Interfering, Bone Morphogenetic Protein Receptors, Type II, Type II, Mice, Rare Diseases, Genetic, Protein Domains, Genetics, Neurites, 2.1 Biological and endogenous factors, Animals, Humans, Autistic Disorder, Phosphorylation, Crosses, Genetic, Pediatric, Mice, Knockout, Neurons, Neurosciences, Brain, Lim Kinases, Bone Morphogenetic Protein Receptors, Biological Sciences, Brain Disorders, Mental Health, Drosophila melanogaster, HEK293 Cells, Gene Expression Regulation, Biochemistry and cell biology, Fragile X Syndrome, Neurological, RNA, Biochemistry and Cell Biology, Signal Transduction, Plasmids
Cofilin 1, 570, Heterozygote, Intellectual and Developmental Disabilities (IDD), Knockout, Prefrontal Cortex, Crosses, Small Interfering, Bone Morphogenetic Protein Receptors, Type II, Type II, Mice, Rare Diseases, Genetic, Protein Domains, Genetics, Neurites, 2.1 Biological and endogenous factors, Animals, Humans, Autistic Disorder, Phosphorylation, Crosses, Genetic, Pediatric, Mice, Knockout, Neurons, Neurosciences, Brain, Lim Kinases, Bone Morphogenetic Protein Receptors, Biological Sciences, Brain Disorders, Mental Health, Drosophila melanogaster, HEK293 Cells, Gene Expression Regulation, Biochemistry and cell biology, Fragile X Syndrome, Neurological, RNA, Biochemistry and Cell Biology, Signal Transduction, Plasmids
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