ER Sheets Get Roughed Up
Authors: Barlowe, Charles;
pmid: 21111224
ER Sheets Get Roughed Up
Abstract
The molecular machinery that shapes the endoplasmic reticulum's (ER's) membrane into ordered networks of "smooth" tubules and "rough" sheets is poorly defined. Shibata et al. (2010) now report that sheet-inducing proteins, such as Climp-63, are enriched in the "rough" ER by their association with membrane-bound ribosomes, whereas curvature-inducing proteins localize at highly bent edges of membrane sheets.
Related Organizations
- Department of Biochemistry Hong Kong
- Dartmouth College United States
- Department of Biochemistry Switzerland
- Dartmouth Medical School
Keywords
Biochemistry, Genetics and Molecular Biology(all)
Biochemistry, Genetics and Molecular Biology(all)
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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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