Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death
Copyright policy )Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death
Neurotropic viral infections are an increasingly common cause of immediate or delayed neuropsychiatric sequelae, cognitive impairment, and movement disorders or, in severe cases, death. Given the highest reported disability-adjusted life years and mortality rate worldwide, a better understanding of molecular mechanisms for underlying clinical manifestations like AFP will help in development of more effective tools for therapeutic solutions.
Male, Interferon Regulatory Factor-7, Motor Activity, Microbiology, Mice, Animals, Humans, motor neuron, pattern-recognition receptor RIG-I, Encephalitis Virus, Japanese, Motor Neurons, Cell Death, Neuromuscular Diseases, Vesiculovirus, neurotropic virus, Myelitis, QR1-502, cell death, Central Nervous System Viral Diseases, DEAD Box Protein 58, Female, Interferon Regulatory Factor-3, acute flaccid paralysis, Research Article
Male, Interferon Regulatory Factor-7, Motor Activity, Microbiology, Mice, Animals, Humans, motor neuron, pattern-recognition receptor RIG-I, Encephalitis Virus, Japanese, Motor Neurons, Cell Death, Neuromuscular Diseases, Vesiculovirus, neurotropic virus, Myelitis, QR1-502, cell death, Central Nervous System Viral Diseases, DEAD Box Protein 58, Female, Interferon Regulatory Factor-3, acute flaccid paralysis, Research Article
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