Data of natural plant species of Sterlitamak (Republic of Bashkortostan) are presented. The city is the part of the Southern Bashkortostan urban aglomeration and among three biggest in Republic. Sterlitamak has population about 276 000. There are large oil refineries, another industrial large transport infrastructure facilities. Dataset is prepared on the base of long years field researches by Golovanov Ya. M. (2013 - 2015). Technical training of the dataset was carried out by Lebedeva M.V. and Drap M. N. Herbarium samples are stored in the herbarium collections of the South Ural Botanical Garden Institute and the Ufa Institute of Biology (UFA). The dataset include one table of species occurrences and contains 3102 record vegetation plots, 198 species. It present occurrences of species in different types of habitats (antropogenic transformed and semi-natural). There are both woody and herbaceous species in dataset. This dataset present third part of urban flora data of South part of Bashkortostan. You can find previous parts through the links: Alien plants of Sterlitamak - https://doi.org/10.15468/sghwhv Alien plants of Salavat - https://doi.org/10.15468/xceg9u